Chemokine C-X-C-Motif Receptor 3 (CXCR3)
other names:CD183; CKR-L2; CMKAR3; GPR9; IP10r; IP10-R; Mig-R; MigR; G Protein-Coupled Receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor
CD183 (CXCR3) is a multi-pass type-3, 7 span 368 aa glycoprotein. It contains an extracellular domain which contains 3 potential amino-glycosylation sites, 7 putative transmembrane-spanning domains and an intracellular carboxyl-terminal regions which has 3 intracellular loop regions.
The intracellular carboxyl-terminal region contains 10 Thr/Ser residues that may become phosphorylated during CD183-mediated signaling. The DRYLAIVHA-motif in the 2nd intracellular loop is the most highly conserved sequence element in chemokine receptors. CD183 is a chemokine receptor which are G-proteins coupled receptors. CD183 shares a 30% identity with CD181 (CXCR1) and CD182 (CXCR2).
https://dldevelop.com/Research-reagent/dl-cxcr3-hu.html
https://dldevelop.com/Research-reagent/dl-cxcr3-mu.html
CD183 (CXCR3) is a multi-pass type-3, 7 span 368 aa glycoprotein. It contains an extracellular domain which contains 3 potential amino-glycosylation sites, 7 putative transmembrane-spanning domains and an intracellular carboxyl-terminal regions which has 3 intracellular loop regions.
The intracellular carboxyl-terminal region contains 10 Thr/Ser residues that may become phosphorylated during CD183-mediated signaling. The DRYLAIVHA-motif in the 2nd intracellular loop is the most highly conserved sequence element in chemokine receptors. CD183 is a chemokine receptor which are G-proteins coupled receptors. CD183 shares a 30% identity with CD181 (CXCR1) and CD182 (CXCR2).
https://dldevelop.com/Research-reagent/dl-cxcr3-hu.html
https://dldevelop.com/Research-reagent/dl-cxcr3-mu.html
